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[064] Citation: C.P. Chou, B. Hannaford, 'Dual Stable Point Model of Muscle Activation and Deactivation,'
Biological Cybernetics, vol. 66, pp. 511-523, 1992.
Abstract
Two dynamic models of muscle activation and deactivation based
on the concepts of ion transport, reaction rates, and muscle mechanics are
proposed. Storage release and uptake of calcium by the sarcoplasmic
reticulum, and a two-step chemical reaction of calcium and troponin are
included in the first model. This is a concise version of the complex
chemical reactions of muscle activation and deactivation in sarcoplasm.
The second model is similar to the first, but calcium-troponin reactions
are simplified into two non-linear rates functions. Due to these nonlinear
dynamics, the second model can explain the catch-like enhancement of
isometric force response. Simulation results which match experimental data
are shown. Also, two new phenomena which need further experiment to verify
are predicted by the second model.
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Updated: Tue Jul 15 23:54:48 2008
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